Anal Intraepithelial Neoplasia (AIN) Treatment

If isolated AIN is identified this is usually treated by excision. This can be carried out as a day case under a short anaesthetic. The affected area off skin is removed.
The wound is usually left open to heal by itself.
For further advice about looking after the area after the surgery, patients can see our advice leaflet  “Caring for yourself after minor anal surgery” which can be found in the Patient Information Section of the website.

Areas of AIN I or II do not normally require any treatment other than careful observation.

Where the AIN III changes are extensive (multifocal) the surgeon will recommend removing any suspicious ulcerated or raised areas. Some topical preparations such as Imiquimod may be beneficial. In very rare cases the surgeons may consider removing all of the skin around the anus in this case a skin graft would be required.
Very occasionally if left untreated anal cancer can develop.
Follow-up visits to the clinic are required to ensure that the anal skin can be closely monitored. Further biopsies may be required.


What are the next steps?
If you think you have this condition or any of these symptoms
you will need to seek medical advice.
For more information or to make an appointment.
Contact birmingham bowel clinic on 0845 241 7762
or email
If you have private medical care or wish
to pay to see a consultant.
Take this factsheet along to your own
GP and request a referral to one
of our consultants
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Mr Ismail, I wanted to thank you for performing the HALO procedure last June. You cannot imagine the difference it has made to my life. I had been suffering with Haemorrhoids for more than twenty years. ”
Mrs Karen Osgood. February 2011